70M Adults with sleep disorders (U.S .) 1 in 5 Adults regularly use sleep aids 35% Rate their sleep as fair or poor 7 Natural supplements backed by research Before you reach for another bottle of Ambien — or scroll past yet another blog that just lists supplements without any real depth — understand this: the research landscape on natural sleep aids has changed dramatically in the past two years. A comprehensive 2024 literature review published in Psychiatry Investigation examined dozens of clinical trials and identified a handful of supplements with genuinely promising evidence behind them. This article breaks down exactly what works, why it works, and the actual dosages researchers used — no guesswork, no hype. No. 01 Melatonin The gold standard of sleep supplements Melatonin is a hormone your pineal gland naturally produces to signal your body that it's time to sleep. It's ...